Sleep Disorders

Restless Leg Syndrome

Restless Leg Syndrome (RLS), also known as Willis-Ekbom Disease, is a neurological disorder characterized by an uncontrollable and often uncomfortable urge to move the legs. People with RLS typically experience symptoms during periods of rest or inactivity, such as when they’re sitting or lying down, and the sensations are usually relieved by movement. These sensations are often described as tingling, crawling, itching, burning, or aching feelings deep within the legs.

The symptoms of RLS tend to worsen in the evening and at night, which can lead to difficulty falling asleep or staying asleep. This can result in sleep disturbances and overall reduced quality of life due to the disruption of normal sleep patterns.

Symptoms of RLS:

RLS is characterized by a distinctive set of symptoms that primarily affect the legs and are often more pronounced during periods of rest or inactivity, particularly in the evening and at night. The key symptoms of RLS include:

  • Uncomfortable Sensations: People with RLS often experience unusual sensations in their legs. These sensations are often described using terms like tingling, crawling, itching, burning, throbbing, or aching. These sensations can be deep within the legs and are sometimes difficult to describe accurately.
  • Urge to Move: The uncomfortable sensations in the legs are accompanied by an irresistible urge to move the legs in order to alleviate the discomfort. This urge tends to be most intense when the person is at rest, such as when sitting or lying down. Movement, such as walking or stretching, typically brings relief.
  • Worsening at Night: RLS symptoms usually worsen in the evening and night, which can lead to sleep disturbances. This pattern of worsening symptoms in the evening and during periods of rest is a distinguishing feature of RLS.
  • Temporary Relief from Movement: Engaging in physical activity or movement provides temporary relief from the uncomfortable sensations. However, the relief may be short-lived, and the sensations may return once the person stops moving.
  • Symptoms in Both Legs: RLS typically affects both legs, although the sensations may be more pronounced in one leg than the other.
  • Impact on Sleep: RLS symptoms can significantly interfere with sleep, making it difficult for affected individuals to fall asleep or stay asleep. As a result, RLS can contribute to insomnia and sleep deprivation.

It’s important to note that the symptoms of RLS can vary in intensity and frequency from person to person. Some individuals may experience only occasional discomfort, while others may have more severe and frequent symptoms that significantly affect their daily lives. If you suspect you have RLS based on the symptoms described above, it’s advisable to seek medical advice for proper diagnosis and management.

Causes of RLS

While the exact cause of RLS is not fully understood, it is believed to have a genetic component, as it often runs in families. Additionally, certain medical conditions like iron deficiency, kidney disease, diabetes, and pregnancy, as well as the use of certain medications, can exacerbate or trigger RLS symptoms. It’s also thought that abnormalities in the brain’s dopamine pathways play a role in the development of RLS.

Diagnosis and Treatment of RLS

Diagnosing and treating Restless Leg Syndrome (RLS) involves a combination of clinical evaluation, medical history assessment, and, if necessary, further tests. Here’s an overview of the diagnostic and treatment process for RLS:


Diagnosing RLS involves a careful evaluation of the patient’s symptoms and medical history. There are no specific laboratory tests or imaging studies that can definitively diagnose RLS, so the diagnosis is primarily based on the following criteria:

  • Symptoms: The key symptoms of RLS, including uncomfortable leg sensations and the urge to move the legs to relieve discomfort, must be present.
  • Timing and Patterns: Symptoms typically worsen during periods of rest and inactivity, especially during the evening and night.
  • Exclusion of Other Conditions: Other medical conditions that could mimic or contribute to RLS symptoms, such as peripheral neuropathy, circulation problems, and certain metabolic disorders, should be ruled out.

If you are experiencing symptoms of Restless Leg Syndrome (RLS), schedule a consultation with Premier Neurology today. Our neurologists specialize in understanding and treating disorders of the nervous system, which includes conditions affecting the brain, spinal cord, and peripheral nerves. RLS is a neurological disorder with distinct sensory and movement-related components, and our neurologists possess the expertise to comprehensively evaluate your symptoms, perform relevant diagnostic tests, and differentiate RLS from other conditions that may mimic its presentation.


The treatment of RLS aims to alleviate symptoms and improve the patient’s quality of life. Treatment strategies can vary depending on the severity of symptoms and their impact on daily functioning. Some common approaches include:

Lifestyle Changes:

  • Regular exercise can help reduce RLS symptoms. However, vigorous exercise close to bedtime should be avoided.
  • Establishing good sleep habits and maintaining a regular sleep schedule can be beneficial.
  • Avoiding caffeine, alcohol, and tobacco, especially in the evening, may help alleviate symptoms.
  • Hot or cold baths, massage, and relaxation techniques might provide temporary relief.

Dietary Changes:

  • Addressing any deficiencies in iron, folate, and magnesium, which can exacerbate RLS, may be recommended.


  • Dopamine agonists, which are medications that increase dopamine levels in the brain, are often prescribed. These medications can help alleviate RLS symptoms by affecting the neurological pathways involved.
  • Other medications, such as opioids, anticonvulsants, and certain medications used to treat Parkinson’s disease, might be considered if dopamine agonists are not effective or if there are concerns about side effects.
  • In some cases, medication to improve sleep quality might be prescribed.

Medical Treatments:

  • For individuals with severe RLS symptoms that significantly impact their quality of life and do not respond well to other treatments, more advanced options like nerve stimulation therapies or intravenous iron infusion might be considered.
  • Medical marijuana may also be used to alleviate symptoms of RLS

The specific treatment approach is highly individualized, and patients should work closely with a healthcare professional to determine the most suitable treatment plan. Monitoring and adjusting treatments as needed based on the patient’s response and any potential side effects are important aspects of managing RLS effectively. If you suspect you have RLS, it’s recommended to seek guidance from a medical professional to receive an accurate diagnosis and appropriate treatment recommendations.